3-Hydroxymethylpyrrolidine-1-carboxylic acid benzyl ester
1-Cbz-3-hydroxymethylpyrrolidine
CAS: 315718-05-9
Molecular Formula: C13H17NO3
3-Hydroxymethylpyrrolidine-1-carboxylic acid benzyl ester - Names and Identifiers
| Name | 1-Cbz-3-hydroxymethylpyrrolidine |
| Synonyms | 1-CBZ-DL-BETA-PROLINOL 1-CBZ-3-HYDROXYMETHYLPYRROLIDINE 1-Cbz-3-hydroxymethylpyrrolidine 3-HYDROXYMETHYL-1-CBZ-PYRROLIDINE benzyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate benzyl 3-(hydroxyMethyl)pyrrolidine-1-carboxylate 3-Hydroxymethylpyrrolidine-1-carboxylic acid benzyl ester 1-Pyrrolidinecarboxylic acid, 3-(hydroxymethyl)-, phenylmethyl ester |
| CAS | 315718-05-9 |
| InChI | InChI=1/C13H17NO3/c15-9-12-6-7-14(8-12)13(16)17-10-11-4-2-1-3-5-11/h1-5,12,15H,6-10H2 |
3-Hydroxymethylpyrrolidine-1-carboxylic acid benzyl ester - Physico-chemical Properties
| Molecular Formula | C13H17NO3 |
| Molar Mass | 235.28 |
| Density | 1.196±0.06 g/cm3(Predicted) |
| Boling Point | 382.0±25.0 °C(Predicted) |
| Flash Point | 184.8°C |
| Vapor Presure | 1.62E-06mmHg at 25°C |
| pKa | 14.93±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.56 |
3-Hydroxymethylpyrrolidine-1-carboxylic acid benzyl ester - Introduction
It is an organic compound whose chemical structure has a hydroxymethyl group (OH) and a protecting group (Cbz) attached to the third carbon of the pyrrolidine ring.
Properties: It is a solid, its appearance is white or similar to white crystals, and has a special smell. It is stable at room temperature and soluble in some organic solvents such as methanol and dichloromethane.
Uses: It is an important organic synthesis intermediate and is widely used in organic chemical synthesis. It is often used as a starting material for the synthesis of other compounds, such as synthetic drugs, the synthesis of natural products, and synthetic ligands.
preparation method: There are many preparation methods. The common method is to react pyrrolidine with Rhodamine B(Rhodamine B) at a certain concentration, and then add oxidizing sodium nitrite (NaNO2) the oxidation reaction is carried out, and finally the target product is obtained by purification and crystallization.
Safety information: It is stable under normal operating conditions, but care should be taken to avoid contact with skin, eyes and inhalation of gases. Personal protective measures such as gloves and goggles should be taken during use. Specific handling and storage requirements need to be understood and noted in detail in accordance with safety data sheets or relevant chemical information. At the same time, the correct laboratory safety operation specifications should be followed during use.
Properties: It is a solid, its appearance is white or similar to white crystals, and has a special smell. It is stable at room temperature and soluble in some organic solvents such as methanol and dichloromethane.
Uses: It is an important organic synthesis intermediate and is widely used in organic chemical synthesis. It is often used as a starting material for the synthesis of other compounds, such as synthetic drugs, the synthesis of natural products, and synthetic ligands.
preparation method: There are many preparation methods. The common method is to react pyrrolidine with Rhodamine B(Rhodamine B) at a certain concentration, and then add oxidizing sodium nitrite (NaNO2) the oxidation reaction is carried out, and finally the target product is obtained by purification and crystallization.
Safety information: It is stable under normal operating conditions, but care should be taken to avoid contact with skin, eyes and inhalation of gases. Personal protective measures such as gloves and goggles should be taken during use. Specific handling and storage requirements need to be understood and noted in detail in accordance with safety data sheets or relevant chemical information. At the same time, the correct laboratory safety operation specifications should be followed during use.
Last Update：2024-04-09 21:11:58
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Product Name: 1-CBZ-3-HYDROXYMETHYLPYRROLIDINE Visit Supplier Webpage Request for quotation
CAS: 315718-05-9
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QQ: 3008007409
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CAS: 315718-05-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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